Immunological Aspects of Skin Diseases

Immunological Aspects of Gastrointestinal Diseases

Immunological aspects of age-related diseases

The proportion of elderly people rises in the developed countries. The increased susceptibility of the elderly to infectious diseases is caused by immune dysfunction, especially T cell functional decline. Age-related hematopoietic stem cells deviate from lymphoid lineage to myeloid lineage. Thymus shrinks early in life, which is followed by the decline of naïve T cells. T-cell receptor repertoi...

Psychoneuroimmunologic aspects of skin diseases.

As mental and psychological issues are important in the development of many dermatologic diseases, these factors are of special interest in research. Psychoneuroimmunology is the study of interaction between psychological processes and the nervous and immune systems of the human body, and it was comprehensively described for the first time about 30 years ago. Communication between the mind and ...

Immunological skin diseases: Boundaries and relationships

About half of skin diseases are immune-related. Immunological skin diseases are crudely divided into infectious, allergic, autoimmune and other types based on the etiology, pathogenesis and immune responses. While their distinction is not absolute, cause-effect and inter-relationship exist among them. This review focuses on the intrinsic associations among different categories of skin immune di...

Mast cells and immunological skin diseases.

Mast cells play an important role in both adaptive and innate immunity, and a large body of literature demonstrates their functions in skin immunity. This article reviews the literature on the role of this cell type in the pathogenesis of a number of immunological skin diseases, including contact dermatitis, atopic dermatitis, immunobullous disease, scleroderma, and chronic graft-vs.-host disea...